Elisa Crisci is a viro-immunologist who has studied swine virology and immunopathology since her DVM degree at the University of Bologna, Italy.
Crisci completed her master’s degree and PhD, and also learned how to handle biolevel 3 zoonotic pathogens at the Centre de Recerca en Sanitat Animal (CRESA) in Barcelona, Spain. During her studies, she focused on animal host-virus interactions and virus-based vaccine vectors for animal diseases, and worked with different swine viruses including circovirus, influenza virus, porcine reproductive and respiratory syndrome virus (PRRSV), foot-and-mouth disease virus (FMDV) and classical swine fever.
After her PhD, Crisci used the pig as a large animal model for immune cell therapy, and in 2013 she joined the molecular virology division of Linköping University, Sweden, to focus on human virology using techniques such as new generation sequencing.
In 2017, she returned to veterinary virology and joined the French National Institute for Agricultural Research (INRA) in Paris, France. Later in 2018, she joined the Department of Population Health and Pathobiology at NC State’s College of Veterinary Medicine as an assistant professor in virology to continue her work on virus-host interactions in pigs, with a focus on the impact of influenza and PRRSV on swine production.
Alongside her research, Crisci works in applied virology with companies such as Fort Dodge, and helps develop research collaborations with commercial industries to improve swine production and food security.
Global Health Research Fields
- Swine viral infectious diseases
Main Areas of Expertise
- Large animal models (pig)
- Porcine viruses including circovirus, influenza virus and porcine reproductive and respiratory syndrome virus (PRRSV)
- Biolevel 3 zoonotic pathogens
- Virus-host relationships
- Innate immunity
Global Health Research Interests
- Swine viral infections and their impact on swine production and food security
Countries of Experience
- Examining virus-host interactions in porcine diseases, particularly influenza and PRRSV, to improve porcine production and food security
- French National Institute for Agricultural Research (INRA), Paris | France
- Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CIB CSIC) | Spain
- Linköping University, Linköping | Sweden
Bordet E, Maisonnasse P, Renson P, Bouguyon E, Crisci E, Tiret M, Descamps D, Bernelin-Cottet C, Urien C, Lefèvre F, Jouneau L, Bourry O, Leplat JJ, Schwartz-Cornol I, Bertho N. Porcine alveolar macrophage-like cells are pro-inflammatory pulmonary intravascular macrophages that produce large titers of Porcine Reproductive and Respiratory Syndrome Virus. Sci Rep 2018 Jul; 8(1): 10171 (Pubmed)
Bordet E, Blanc F, Tiret M, Crisci E, Bouguyon E, Renson P, Maisonnasse P, Bourge M, Leplat JJ, Giuffra E, Jouneau L, Schwartz-Cornol I, Bourry O, Bertho N. Porcine Reproductive and Respiratory Syndrome Virus type 1.3 Lena triggers conventional dendritic cells 1 activation and T helper 1 immune response without infecting dendritic cells. Front Immunol 2018 Oct; 9: 2299 (Pubmed)
Maisonnasse P, Bouguyon E, Bourge M, Piton G, Ezquerra A, Deloizy C, Urien C, Leplat JJ, Simon G, Chevalier C, Vincent-Naulleau S, Crisci E, Montoya M, Schwartz-Cornil I, Bertho N. Pig as a biomedical model: Putting the porcine lung dendritic cells/macrophages network into light. Rev Mal Respir 2017 Jan; 34: A328 (ScienceDirect)View more on Google Scholar
Global Health Memberships