Antimicrobial Resistance

Antimicrobial Resistance

Research Focus Area

Global Health Research

 

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Antimicrobial resistance (AMR) is one of the greatest health threats facing mankind today. 

With our global partners, we are tackling AMR by investigating the molecular epidemiology of drug-resistant strains across multiple hosts, studying transmission of resistance between animals, humans and the environment, developing new diagnostics for early detection, and studying the impact of the gut microbiome on colonization resistance against drug-resistant strains. 

 

Faculty

 

 

Ongoing Projects


Impact of antimicrobial concentrations in the gastrointestinal tract of cattle on antimicrobial resistance in enteric bacteria.

INVESTIGATOR

Derek Foster

COLLABORATORS:

FARAD


“Healthy Living for Healthy Ageing: A Global Focus” – a collaboration within the University Global Partnership Network.

INVESTIGATOR:

Sid Thakur

COLLABORATORS:

  • University of São Paulo | Brazil 
  • University of Surrey | United Kingdom
  • University of Wollongong | Australia


Establishing a surveillance system to monitor AMR profile of enteric pathogens in humans and food animals in India.

INVESTIGATOR:

COLLABORATORS:

  • Gobind Ballabh Pant University of Agriculture and Technology | India
  • Indian Council of Agriculture Research-Central Institute of Fisheries Technology | India
  • Indian Council of Agriculture Research-National Research Center on Meat | India
  • Institute of Microbial Technology | India
  • Post Graduate Institute of Medical Research | India


AMR monitoring technology in pathogenic bacteria isolated from animal products based on gene identification.

INVESTIGATOR:

COLLABORATORS:

Shandong Academy of Agricultural Sciences | China


Monitoring drug resistance in Salmonella, Campylobacter, Escherichia coli and Enterococcus spp. in retail meats. 

INVESTIGATORS:

COLLABORATORS:

  • NIH
  • FDA


Whole genome sequencing-based surveillance of bacterial pathogens isolated from food and from the environment.

INVESTIGATORS:


Antimicrobial use and prescribing behaviors by health professionals and livestock owners in Ethiopia.

INVESTIGATOR:

Andy Stringer

COLLABORATORS:

Aklilu Lemma Institute of Pathobiology, Addis Ababa University | Ethiopia


The ESBL Tricycle AMR Surveilance Project: A simple, One Health approach to global surveillance.

INVESTIGATORS:

COLLABORATORS:

  • Jorge Matheu, WHO food safety and zoonoses department | Switzerland

PROJECT SUMMARY:

By providing training and establishing new surveillance laboratories, this project aims to implement a simplified, integrated, trans-sectoral surveillance system of bacterial resistance to antibiotics across the globe. Read more.


Examining antimicrobial resistance in gastrointestinal bacteria isolated from animal populations.

INVESTIGATOR:

Casey M. Theriot

COLLABORATORS:

NC State University, North Carolina | United States

  • Megan Jacob, Department of Population Health and Pathobiology
 


UGPN consortium to tackle the global burden of antimicrobial resistance.

INVESTIGATOR:

Sid Thakur

COLLABORATORS:

  • University of São Paulo | Brazil 
  • University of Surrey | United Kingdom
  • University of Wollongong | Australia


GRIP: The NCSU/RTI Program In Genetic Discovery and Prediction (PGDP).

INVESTIGATOR:

Sid Thakur

COLLABORATORS:

  • NC State
  • RTI


Studying the integration of antimicrobial and anti-fungal peptides with nonwoven substrates.

INVESTIGATOR:

Lauren Schnabel

 

 

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